Clinico-epidemiological Profile of Multisystem Inflammatory Syndrome in Children

Introduction: MIS-C (multisystem Inflammatory Syndrome in Children) has been reported as a complication of post COVID infection in paediatric age group. The presentation of this syndrome includes constellation of clinical features. This study aims to inquire about the incidence of these symptoms in the clinical setting.

Methods: Cross sectional observation study in a tertiary care hospital of North India and clinic-epidemiological profile of children with MIS-C was studied.

Results: Fever was the most common symptom (100%) followed by gastrointestinal symptoms (80%). All of them presented with raised markers of acute inflammation (CRP, D-Dimer etc). Cardiovascular complications included shock (36%) with Left Ventricular dysfunction (22%), myocarditis (20%), coronary dilatation (16%), and pulmonary edema (10%). Rash was noticed in 20% of the cases and bleeding was seen in 12% of the cases. Few patients had other rare presentations also.

Conclusion: Patients with such clinical features without evidence of tropical infection should be kept as a possibility of MIS-C.