Deregulation of Circular RNAs in Cancer From the Perspectives of Aberrant Biogenesis, Transport and Removal

Wu, Qiongqiong and Li, Peiyao and Wu, Minghua and Liu, Qiang (2019) Deregulation of Circular RNAs in Cancer From the Perspectives of Aberrant Biogenesis, Transport and Removal. Frontiers in Genetics, 10. ISSN 1664-8021

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Official URL: https://doi.org/10.3389/fgene.2019.00016

Abstract

CircRNAs (circular RNAs) are a class of RNAs generated from circularization with multiple novel functions. Recent studies have revealed the aberrant expression and aberrant functions of circRNAs in various tumors; thus, circRNAs have been recognized as promising cancer biomarkers. However, the underlying mechanisms behind their aberrant expression and functions remain unclear. In this review, we discuss at length the cancer-specific deregulation of circRNAs and the potential underlying aberrant events in circRNA biogenesis, localization and removal in cancer cells.

Item Type:	Article
Subjects:	OA Open Library > Medical Science
Depositing User:	Unnamed user with email support@oaopenlibrary.com
Date Deposited:	09 Feb 2023 08:11
Last Modified:	13 Feb 2024 03:52
URI:	http://archive.sdpublishers.com/id/eprint/225

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