Severe Anemia Secondary to Valproic Acid Therapy in a Twelve Year Old Girl

Balagopal, Krishnan and Mathew, M. A. and Bose, Binu Mary and Alex, Jim and Ismail, Shamima and Nair, Nimisha S. (2021) Severe Anemia Secondary to Valproic Acid Therapy in a Twelve Year Old Girl. Asian Journal of Case Reports in Medicine and Health, 5 (2). pp. 24-28.

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Abstract

Background: Sodium Valproate is one of the commonest antiepileptic drugs used in the paediatric age group. Haematological side effects of Valproate though rare are an important cause of morbidity. These can include anemia, red cell aplasia and thrombocytopenia. Early recognition of this complication is important for proper management.

Objective: To describe a case of severe anemia caused by chronic therapy with sodium Valproate in a twelve year old girl with seizure disorder.

Presentation of Case: We describe here a case of a twelve year old girl who was a known case of epilepsy on Valproate therapy presenting with severe anaemia. Haematological parameters normalized after stopping Valproate. Through this report, we wish to highlight the importance of periodic monitoring of blood counts in every patient on long term Valproate therapy.

Item Type: Article
Subjects: OA Open Library > Medical Science
Depositing User: Unnamed user with email support@oaopenlibrary.com
Date Deposited: 21 Mar 2023 06:49
Last Modified: 16 Sep 2023 04:59
URI: http://archive.sdpublishers.com/id/eprint/208

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