Comparative Analysis on the Antimycotic Effect of Azadiracta indica and Jatropha curcas on Curvularia Species

This study was carried out to determine the phytochemical properties and the antimycotic effect of Jatropha curcas and Azadiracta indica leaves on Curvularia species. Isolation and identification of the fungal isolates were carried out using standard conventional method. Maceration technique was employed for crude extraction from the plant. The phytochemical tests were carried out using standard conventional methods. Agar well diffusion method was used to determine the susceptibility of the isolates. Phytochemical tests of A. indica revealed the presence of flavonoids, phenols, saponins, tannins, phenols, and glycosides. Jatropha curcas showed the presence of glycoside, tannins, saponin steroids and phenols. The antifungal activity of Azadiracta indica and Jatropha curcas on Curvularia species, the ethanol extract of Azadiracta indica showed more antifungal activity with highest percentage inhibition of 50.56±0.84c at 20% extract concentration, and Aqueous extract was 40.00±0.55b at 20%. The aqueous extract of Jatropha curcas showed more antifungal activity of 50.55±0.05c at 20% while that of ethanol extract was 35.55±0.54a at 20% extract concentration. The synergestic antifungal activity of the plants revealed that ethanolic extract had more antifungal effect of 57.54±0.56c at 20% concentration and that of the aqeous extract showed more activity of 45.89±0.50b at 20%. There was significant difference (P<0.05) between the ethanoic and aqueous extracts of the plants. The Minimum Inhibitory Concentration (MIC) and Minimum Fungicidal Concentration (MFC) of Jatropha curcas on Curvularia Species showed the MIC at 250 mg/ml extract concentration for both ethanol and aqueous extracts against Curvularia Species. The ethanol and aqueous extract of Jatropha curcas occurred has no fungicidal effect against Curvularia Species.