Blind Eye Associated with Osteosarcoma

We report the case of a 10 year old girl with a late diagnosis of a high grade osteosarcoma (Stage IIb) of the right femur in a low income setting. The diagnosis could clinically have been made much earlier if the observation of an enucleated congenitally blind left eye due to a probable retinoblastoma was known to be associated with osteosarcoma. Screening of at-risk families and close surveillance of affected individuals for these heritable genetic predisposition syndromes may permit earlier diagnosis and more effective treatment of osteosarcoma in these populations.